Investigations of emerging zoonotic diseases. Issues in public health. American biological safety association 2. Handling of large experimental animals infected with a risk group 4 virus.
Please click here for a PubMed list of publications. Alegre M, Vincent JL. Dopamine dependence in hypocalcemic patients. Effect of a single amino acid mutation on the activating and immunosuppressive properties of a "humanized" OKT3 monoclonal antibody. Sequence and functional characterization of feline interleukin 2.
Serum cytokine levels in human septic shock. Relation to multiple-organ failure and mortality. A non-activating "humanized" anti-CD3 monoclonal antibody retains immunosuppressive properties in vivo. Prevention of the humoral response induced by an anti-CD3 monoclonal antibody by Deoxyspergualin in a murine model.
Severe combined immunodeficient mice engrafted with human splenocytes have functional human T cells and reject human allografts. Bioactivity of recombinant feline interleukin-2 on human and feline leukocytes. An anti-murine CD3 monoclonal antibody with a low affinity for Fcg-receptors suppresses transplantation responses while minimizing toxicity and immunogenicity.
Production of IL in patients with circulatory shock; role in monocyte dysfunction. CTLA-4 interacts with the medium chain of clathrin associated proteins and undergoes clathrin mediated endocytosis. Tissue distribution and biochemical characterization of murine CD1 molecules.
Impaired negative selection in CDdeficient mice. Regulation of cytotoxic T lymphocyte-associated molecule-4 by Src kinases. The administration of an anti-CD3 mAb in mice differentially regulates the production of cytokines upon restimulation: Downregulation of antigen presenting cell functions following administration of mitogenic anti-CD3 monoclonal antibodies.
In vitro characterization of five humanizedOKT3 effector function variant antibodies. Different mechanisms of cardiac allograft rejection in wildtype and CDdeficient mice.
Confounding factors complicate conclusions in aly model.
Nature Medicine letter7: Modified anti-CD3 therapy in psoriatic arthritis: Secondary lymphoid organs are important but not absolutely required for allograft responses. Accompanying editorial by F.
Where is the alloimmune response initiated? Genes and Development, Modulation of tryptophan catabolism by regulatory T cells.
Accompanying editorial by Karen Honey. The actin cytoskeleton regulates calcium dynamics and NFAT nuclear duration. B7-H1 costimulation promotes T cell-mediated autoimmune diabetes and islet transplantation rejection. Transplanted islets from lpr mice are resistant to autoimmune destruction in a model of streptozotocin-induced type I diatetes.
Role of NK cell subsets in cardiac allograft rejection. TLR engagement prevents transplantation tolerance. Donor lymphoid organs are a major site of alloreactive T cell priming following intestinal transplantation. Overexpression of PD-1 in T cells has mild impact on allograft survival. Harnessing negative T cell costimulatory pathways to promote engraftment.
Epidermal Langerhans cells play a major role in skin allograft rejection in mice with NF-kB-impaired T cells. Jump-starting alloreactive T cells with high-activation thresholds-donor Langerhans cells provide the charge. Prevention of transplantation tolerance by bacterial infection with Listeria monocytogenes.
Front Cover of the JI issue.Betty Dodet, Pharm D, PhD is Director of the scientific communication consultancy, Dodet Bioscience (DBS), which specialises in biology, biotechnology and public health. Betty Dodet qualified in pharmacy at the Université Lyon I, France in Veterinary Medicine International is a peer-reviewed, Open Access journal that publishes original research articles and review articles in all areas of veterinary research.
The journal will consider articles on the biological basis of disease, as well as diagnosis, prevention, treatment, and epidemiology.
() Grant Writer and Project Manager Salvazzano Dentro, Italy Grant Writer and Project Manager Jan Parys, Ph.D. () Katholieke University, Department of Physiology, Leuven, Belgium Professor Erik Rader, Ph.D.
Dodet Bioscience, Lyon, France 5.
Professeur d’anesthésie réanimation, membre AfroREB, président ONG Association béninoise contre la Rage, Cotonou, Bénin *Both authors contributed equally Corresponding author: Arnaud Tarantola, MD, Msc Head, Epidemiology and Public Health Unit. Search. Barcelona - Spain. The Ecology and Evolutionary History of an Emergent Disease: Hantavirus Pulmonary Syndrome: Evidence from two El Niño episodes in the American Southwest suggests that El Niño–driven precipitation, the initial catalyst of a trophic cascade that results in a delayed density-dependent rodent response, is sufficient to predict heightened risk for human contraction of hantavirus pulmonary .